Comparison 6. 0 ppm F versus 250 ppm F in children and adolescents (immature permanent dentition).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 D(M)FS closest to 3 years	3	1460	Std. Mean Difference (IV, Random, 95% CI)	‐0.09 [‐0.19, 0.02]
2 D(M)FT	1		Std. Mean Difference (IV, Random, 95% CI)	Subtotals only
3 Proportion developing new caries	2	684	Risk Ratio (M‐H, Random, 95% CI)	1.07 [0.91, 1.27]