Comparison 12. 250 ppm F versus 1000 ppm F in children and adolescents (immature permanent dentition).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 D(M)FS	6	3047	Std. Mean Difference (IV, Random, 95% CI)	‐0.11 [‐0.20, ‐0.02]
2 D(M)FT	3	2087	Std. Mean Difference (IV, Random, 95% CI)	‐0.16 [‐0.27, ‐0.05]
3 Proportion developing new caries	2	676	Risk Ratio (M‐H, Random, 95% CI)	1.00 [0.63, 1.59]