1. Distribution of potential effect modifiers.
| Fluoride concentration | Supervised toothbrushing | Community water fluoridation > 0.5 ppm F | ||
| D(M)FS | D(M)FT | D(M)FS | D(M)FS | |
| 0 ppm F (placebo toothpaste) | 15/61 (25%) | 13/46 (28%) | 6/41 (15%) (unreported 20 studies) |
6/31 (unreported 15 studies) |
| 250 ppm F | 1/4 (25%) | 1/2 (50%) | 1/4 (25%) | 1/2 (50%) |
| 440 to 550 ppm F | No studies | No studies | No studies | No studies |
| 1000 to 1250 ppm F | 4/20 (20%) | 3/7 (43%) | 3/15 (20%) (unreported 5 studies) |
2/7 (29%) |
| 1450 to 1500 ppm F | 2/8 (25%) | 2/2 (100%) | 1/4 (25%) (unreported 4 studies) |
1/2 (50%) |
| 1700 to 2200 ppm F | 0/5 (0%) | 0/1 (0%) | 1/5 (20%) | 0/1 (0%) |
| 2400 to 2800 ppm F | 1/6 (17%) | 0/3 (0%) | 0/3 (0%) (unreported 3 studies) |
0/3 (0%) |
D(M)FS = decayed, missing, filled permanent surfaces; D(M)FT = decayed, missing, filled permanent teeth; F = fluoride; ppm = parts per million.