Table 2. Performance of miRNAs and their combinations to predict disease status in breast cancer.
| Potential predictors | Cut-off value | Sensitivity % | Specificity % | AUC (95% CI) | P |
|---|---|---|---|---|---|
| miR-21 | 1.65 | 51.4 | 83.3 | 0.722 (0.648–0.796) | <0.001 |
| miR-23b | 0.93 | 75.7 | 42.1 | 0.591 (0.511–0.672) | 0.033 |
| miR-190 | 1.02 | 48.5 | 74.6 | 0.576 (0.486–0.665) | 0.089 |
| miR-200b | 2.06 | 60.0 | 75.8 | 0.720 (0.644–0.796) | <0.001 |
| miR-200c | 1.35 | 62.9 | 61.1 | 0.621 (0.538–0.705) | 0.005 |
| 4 miRNAs panel (miR-21, miR-190, miR-200b, miR-200c) | 0.31 | 72.7 | 75 | 0.797 (0.727–0.866) | <0.001 |
AUC, area under the receiver operating curve.