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| TKI | FLT3-WT |
FLT3-ITD |
FLT3-D835Y |
|||
|---|---|---|---|---|---|---|
| Seq. E | Seq. F | Seq. E | Seq. F | Seq. E | Seq. F | |
| SORAFENIB | 8.7 ± 3.5 | 13 ± 11 | 780 ± 300 | 550 ± 81 | 1,800 ± 300 | 3,200 ± 940 |
| QUIZARTINIB | 8.6 ± 1.3 | 32 ± 20 | 190 ± 110 | 266 ± 49 | NA | 4,700 ± 870 |
| CRENOLANIB | 13 ± 3.8 | 1.3 ± 0.92 | 45 ± 14 | 52 ± 8.9 | 15 ± 1.4 | 32 ± 7.9 |
