Table 3.
Univariable Cox regression in whole population | Whole population, adjusted for Masaoka stage | WHO histological type C only, adjusted for age, gender, radiotherapy, and chemotherapy | ||||
---|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
cg05784862 KSR1† | 0.868 (0.814–0.926) | < 0.001 | 0.870 (0.814–0.931) | < 0.001 | 0.852 (0.768–0.945) | 0.003 |
cg07154254 ELF3† | 0.718 (0.611–0.844) | < 0.001 | 0.720 (0.611–0.848) | < 0.001 | 0.674 (0.519–0.874) | 0.003 |
cg02543462 IL1RN† | 0.868 (0.819–0.920) | < 0.001 | 0.870 (0.819–0.923) | < 0.001 | 0.859 (0.798–0.925) | < 0.001 |
cg06288355 RAG1† | 1.202 (1.089–1.328) | < 0.001 | 1.201 (1.085–1.328) | < 0.001 | 1.201 (1.083–1.332) | 0.001 |
†All beta values in each methylation sites were entered into equation as continuous variables