Survival of bacteria in HD-11 chicken macrophages. (A) Ingestion of wild-type strain E058, E058 ΔsodA isogenic mutant, and ReE058 ΔsodA complementation strain by HD-11 cells. The values represent the average data from three independent experiments. The error bars indicate standard deviations. (B) Intracellular growth of bacteria in chicken macrophage HD-11 cells. The intracellular growth of wild-type strain E058, the E058 ΔsodA isogenic mutant, and the ReE058 ΔsodA complementation strain were compared over a 12-h period. Standard errors of the mean for the results from three independent experiments are shown. The asterisks indicate statistically significant differences (**, P < 0.01).