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. 2019 Feb 8;149(3):416–421. doi: 10.1093/jn/nxy290

FIGURE 2.

FIGURE 2

Gene expression of ldlr (A), ubiad(B), vkorc1 (C), hmgcr (D), ggcx (E), and vkorc1l1 (F) in tissues from C57BL/6 male mice aged 4 mo (Young, Y) and 20 mo (Old, O) fed a phylloquinone control diet with or without atorvastatin (Statin, S) for 8 wk. Data are displayed as expression relative to the young control diet group and are presented as mean ± SEM, n = 8. Bars represent 2-group comparisons of interest with endpoints of each bar indicating the 2 groups being compared. Asterisk above a bar denotes significant difference at P < 0.05. vkorc1, vitamin K epoxide reductase complex 1; vkorc1l1, vitamin K epoxide reductase complex 1 like 1; ggcx, gamma glutamyl carboxylase; ubiad, ubiA domain containing protein 1; hmgcr: HMG-CoA reductase; ldlr: low density lipoprotein receptor.