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. 2019 Feb 21;10:136. doi: 10.3389/fneur.2019.00136

Figure 3.

Figure 3

Duration of intraarterial nimodipine treatment with respect to retreatment necessity. A: Illustrative cut-off at 3 days treatment duration, indicating a frequent necessity for retreatment when discontinued prior to completion of this time window; †: Two patients in whom life-supporting measures were suspended due to poor overall condition did not receive retreatment after early (< 72 h) discontinuation; × : Out of four patients requiring retreatment after late discontinuation, three patients represent cases with severe, refractory course with 3–4 treatments or, in one case, an elongated hypoperfusion phase of 18 days, and one patient's reperfusion of the anterior territories was complicated by unilateral hypoplasia of an anterior cerebral artery.