Table 1.

Summary of the pneumococcal genome datasets analyzed in this study.

Location	Genomes (n)	Years of isolation	STsa (n)	CCsb (n)	Serotypes (n)	PCV statusc	Source of data
Reykjavik	986	2009–2014	98	42	31	Pre- and post-PCV10	van Tonder et al., 2015, 2016; Quirk et al., 2018
Southampton	516	2006–2011	128	54	43	Post-PCV7/13	Gladstone et al., 2015
Boston	616	2001–2007	139	56	31	Post-PCV7/13	Croucher et al., 2013
Maela	1,000	2004–2010	215	85	63	PCV naive	Chewapreecha et al., 2014

^aST, multilocus sequence type.

^bCC, clonal complex. The number of Singleton STs (those without any links to another ST) are not included in the total number of CCs, but are as follows: Reykjavik, n = 5; Southampton, n = 4; Boston, n = 3; Maela, n = 36.

^cPCV, pneumococcal conjugate vaccine and 7, 10, and 13 refers to vaccine valency.