Fig. 3.
Cnot3LKO mice display iron-deficiency anemia. Concentrations of red blood cells (RBCs), hemoglobin (Hb), hematocrit (Ht) and reticulocytes were measured in blood from 4-week-old (4 w) (upper graphs), and 7 w and 8 w (lower graphs) control and Cnot3LKO mice (control: n=6 at 4 w, n=4 at 7 w, n=3 at 8 w; Cnot3LKO: n=6 at 4 w, n=3 at 7 w, n=4 at 8 w). MCV, MCH and mean corpuscular hemoglobin concentration (MCHC) were calculated from RBC, Hb and Ht values. Data are mean±s.e.m. *P<0.05, **P<0.01, ***P<0.001.