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Schematic representation of the cellular response to ionizing radiation in Aβ42-induced AD models. Balancing between AKT and p38 pathway activation controls cellular responses to low- or high-dose ionizing radiation. Low-dose ionizing radiation induces beneficial effects against Aβ42-induced apoptosis through activation of AKT signaling and suppression of the p38 pathway in Aβ42-associated AD models.
