Table 2.
GH secretion parameters in offspring of long‐lived families and controls
| Offspring n = 19 | Controls n = 18 | P‐value | |
|---|---|---|---|
| Slow half‐life (minutes) | 16.2 (14.3–18.0) | 15.2 (13.3–17.1) | 0.46 |
| Total secretion (mU L−1 per 24 h) | 172 (128–216) | 238 (193–284) | 0.04 |
| Basal secretion (mU L−1 per 24 h)a | 14.5 (9.8–21.5) | 26.9 (17.9–40.4) | 0.03 |
| Pulsatile secretion (mU L−1 per 24 h) | 151 (113–188) | 191 (152–230) | 0.14 |
| Number of pulses (per 24 h)a | 13.7 (12.1–15.5) | 13.8 (12.1–15.7) | 0.97 |
| Interpulse regularity γ (unitless) | 1.3 (1.2–1.5) | 1.5 (1.3–1.7) | 0.26 |
Unless indicated otherwise, data are presented as mean with 95% confidence interval.
a
Data are presented as geometric mean with 95% confidence interval. Analyzed by linear mixed model adjusted for sex and age.