Fig 7. Effects of fractions from HyE-Ov on antimicrobial innate immune response.
DC (A), M1 (B) and M2 (C) cells (5x105/well) were infected with BCG-lux for 3 hours (MOI 5) and stimulated or not with HyE-Ov or with eight HyE-Ov derived fractions, used at the same concentrations present in the total extract. Mycobacterial growth was evaluated by luminometric analysis after 3 days from stimulation (t0). Data are shown as means ± SD of the ratio t3/t0 of RLU values from triplicate cultures and are representative of at least 2 independent experiments performed on cells from different donors. *p<0.05, **p<0.01 and ***p<0.0001 in comparison with non-stimulated infected cells.