Table 2. Characteristics of 33 confirmed TB patients, stratified by QFT-Plus results.
Characteristics | Total | QFT-Plus (-) | QFT-Plus (+) | p-value |
---|---|---|---|---|
(n = 33) | (n = 15) | (n = 18) | ||
Age (years), median (IQR) | 9.8 (2.3, 13.4) | 6.5 (2.2, 10.4) | 11.5 (2.3, 13.8) | 0.08 |
Age (years) | 0.20 | |||
0–5 | 12 (36.4) | 7 (46.7) | 5 (27.8) | |
6–10 | 6 (18.2) | 4 (26.7) | 2 (11.1) | |
11–15 | 13 (39.4) | 4 (26.7) | 9 (50.0) | |
16–17 | 2 (6.1) | 0 (0.0) | 2 (11.1) | |
Male gender | 17 (51.5) | 8 (53.3) | 9 (50.0) | 0.85 |
BMI z-score ≤-2 | 13 (39.4) | 6 (40.0) | 7 (38.9) | 0.95 |
History of TB | 2 (6.1) | 1 (6.7) | 1 (5.6) | 0.89 |
At least one clinical sign or symptom consistent with TB | 24 (72.7) | 9 (60.0) | 15 (83.3) | 0.13 |
Chest radiograph consistent with TB | 0.01 | |||
No | 8 (24.2) | 5 (33.3) | 3 (16.7) | |
Yes | 18 (54.5) | 4 (26.7) | 14 (77.8) | |
Not done | 7 (21.2) | 6 (40.0) | 1 (5.6) | |
Sputum AFB Smear | 0.09 | |||
Negative | 3 (9.1) | 0 (0.0) | 3 (16.7) | |
Positive | 5 (15.2) | 1 (6.7) | 4 (22.2) | |
Unknown/Not done | 25 (75.8) | 14 (93.3) | 11 (61.1) | |
Sputum culture | <0.001 | |||
Negative | 10 (30.3) | 9 (60.0) | 1 (5.6) | |
Positive | 18 (54.5) | 3 (20.0) | 15 (83.3) | |
Unknown/Not done | 5 (15.2) | 3 (20.0) | 2 (11.1) | |
Biopsy results (both pulmonary and EPTB samples) | <0.001 | |||
Negative | 3 (9.1) | 1 (6.7) | 2 (11.1) | |
Positive | 15 (45.5) | 13 (86.7) | 2 (11.1) | |
Unknown/Not done | 15 (45.5) | 1 (6.7) | 14 (77.8) | |
GenXpert | 0.004 | |||
Negative | 19 (57.6) | 11 (73.3) | 8 (44.4) | |
Positive | 9 (27.3) | 0 (0.0) | 9 (50.0) | |
Unknown/Not done | 5 (15.2) | 4 (26.7) | 1 (5.6) | |
TB site category | <0.001 | |||
Exclusive EPTB | 7 (21.2) | 6 (40.0) | 1 (5.6) | |
Concomitant PTB and EPTB | 7 (21.2) | 6 (40.0) | 1 (5.6) | |
Exclusive PTB | 19 (57.6) | 3 (20.0) | 16 (88.9) | |
Specific TB site (patient may have multiple lesion sites) | ||||
Pulmonary | 26 (78.8) | 9 (60.0) | 17 (94.4) | 0.02 |
Lymph nodes | 9 (27.3) | 7 (46.7) | 2 (11.1) | 0.02 |
Bone | 4 (12.1) | 4 (26.7) | 0 (0.0) | 0.02 |
Pleural | 1 (3.0) | 1 (6.7) | 0 (0.0) | 0.27 |
Values are in frequency and % unless otherwise indicated; IQR, interquartile range; TB, tuberculosis; BCG, Bacille Calmette-Guerin; BMI, body mass index; AFB, Acid- Fast Bacilli; PTB, pulmonary TB; EPTB, extra-pulmonary TB