Figure 3.

REV7 modulates the radioresistance of esophageal squamous cell carcinoma (ESCC) tumor xenografts. A‐B, Growth curve of Eca109 in subcutaneous tumor xenografts. C‐D, Representative images of the volume and weight of tumors originating from ESCC tumor xenografts in nude mice at 8 wk (1 wk postirradiation). The tumor weights are presented as the mean ± SEM of 3 independent experiments. **P < .01, *P < .05. E‐F, Representative immunohistochemistry (IHC) staining of Bax and Bcl2 in the indicated tumor xenografts. Scores or counts of IHC were evaluated by 2 independent observers in a blinded manner and are presented as the mean ± SEM of 3 independent experiments. **P < .01, *P < .05