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Schema representing the main cellular functions and substrates of mTORC2.
Legend: Akt, protein kinase B; FoxO1/3, Forkhead box O1/3; PKC-α, protein kinase C-α; LATS, large tumor suppressor kinase 1; MST1, mammalian sterile 20- like kinase 1; RhoA, Ras homolog gene family, member A; SGK1, serum- and glucocorticoid-induced protein kinase-1; YAP, yes associated protein.
