Fig. 2. XooNet can reconstruct regulatory circuits under control of two-component systems in Xoo.
XooNet with highlights for subnetworks of differentially expressed proteins (DEPs). XooNet links between down-regulated DEPs (blue nodes and edges) and those between up-regulated DEPs (red nodes and edges) in (A) △sreK and (B) △stoS are overlaid on the background of the whole XooNet (white nodes and edges). There were 55 and 53 down-regulated DEPs for △sreK and △stoS, respectively, and 46 and 39 upregulated DEPs for △sreK and △stoS, respectively.