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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Pharmacogenet Genomics. 2019 Apr;29(3):65–68. doi: 10.1097/FPC.0000000000000366

Figure 1.

Figure 1

cg27254601 is associated with improved lung function on inhaled corticosteroids and BOLA2 expression

a) Relative hypermethylation of cg27254601 is associated with an improvement in forced expiratory volume in one second (FEV1) in pediatric asthmatics after initiating inhaled corticosteroids. b) Partial correlation between DNA methylation and gene expression controlling for percentage change in FEV1 after initiating inhaled corticosteroid therapy, age, sex, batch effect, clinic site, and lymphocyte counts (ρ = 0.25, P = 0.02).