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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Brain Behav Immun. 2018 Dec 11;77:66–76. doi: 10.1016/j.bbi.2018.12.006

Figure 7: Poly(I:C) prevents escalation of alcohol intake when alcohol access occurs at peak innate immune activation in males.

Figure 7:

C57BL/6J male mice were injected with saline or poly(I:C) (5mg/kg) every fourth day for a total of eight injections during two-bottle choice, every-other-day drinking (EOD,15%v/v). (A) 3hr delay injection schedule; (B) Ethanol (EtOH) intake (g/kg/24 h); (C) preference for EtOH; (D) total fluid intake. Arrows indicate days when animals received injection; (n=10 per group).