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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Parkinsonism Relat Disord. 2018 Sep 4;60:138–145. doi: 10.1016/j.parkreldis.2018.08.025

Figure 2. Proportional Odds Models – Probability of Start of Mild Impairment for Each PSP Rating Scale Domain Subscore as PSP Rating Scale Total Score Worsens – PSP (all 4 studies) vs CBS (4RTNI) (upper panel), and as CGIds and SEADL Worsen – AL-108–231, 4RTNI, and TAUROS Studies Combined (lower panel).

Figure 2.

Abbreviation: CBS, corticobasal syndrome; CGIds, Clinical Global Impression of Disease Severity; PSP, progressive supranuclear palsy; SEADL, Schwaab and England Activities of Daily Living. Dashed line represents the average score of a patient entering a clinical trial (Table 2); PSPRS=38, SEADL=55, CGIds=4 for PSP patients and 28 for CBS patients.

Note: Link to online version with 95% Cis: https://pspmodel.shinyapps.io/PSP_Progression/