NCT03286959.

Methods	Effect of liners on pulpal outcome and restoration survival after partial caries excavation Trial design: randomised, double‐blind, parallel‐group, controlled trial Location: Postgraduate Institute of Dental Sciences, Rohtak, India
Participants	Inclusion criteria: participant willing to participate in the study; mature permanent mandibular molars with deep dentinal caries involving more than half or 2/3 of dentin Age: 14 to 54 years Exclusion criteria: primary teeth; teeth with irreversible pulpitis (spontaneous pain) or pulp necrosis, chronic periodontitis, cracked tooth, internal or external resorption, calcified canals, associated with sinus tract, and furcation or apical radiolucency; immuno‐compromised, diabetic, pregnant and hypertensive patients; positive history of antibiotic and analgesic use
Interventions	Partical caries removal (PCR) with calcium hydroxide, PCR with resin‐modified glass ionomer cement (RMGIC), and PCR with direct composite (no liner)
Outcomes	Clinical and radiographic success ("presence of positive response to vitality tests, absence of tenderness or spontaneous pain will be considered as clinical signs of success while absence of any radiolucency in periapical or furcation region or root resorptions as radiographic signs of successful outcome"); survival of composite restoration
Notes