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. 2019 Feb 26;13:8. doi: 10.3389/fnbeh.2019.00008

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Copyright © 2019 Bye and McDonald.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Pretraining for group 1 in Experiment 1. Four trial averages of the latency in seconds to find the platform over training 4 days/eight trials per day. Both controls and pre-CPP rats successfully learn over training. (B) Mass training for group 1 in Experiment 1. Two trial averages of the latency in seconds to find the new platform over training 2 h/16 trials. Both controls and CPP rats learn over training. (C) A probe test of trial 1 mass training in group 1 of Experiment 1. The percentage of time spent of the trial length in the pre-training quadrant versus an average of the other three. Both controls and CPP rats display a preference for the pre-trained quadrant. (D) Dorsal and ventral hippocampal cannulation locations for the CPP rats of group 1 in Experiment 1. Error bars 1 ± SE.