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. 2019 Feb 26;13:8. doi: 10.3389/fnbeh.2019.00008

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Copyright © 2019 Bye and McDonald.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) A 30-s probe test immediately after mass training for group 1 in Experiment 1. The percentage of time spent in the mass trained quadrant versus an average of the other three was compared. Both controls and CPP rats displayed a preference for the mass trained quadrant. (B) A 30-s probe test immediately after mass training for group 1 in Experiment 1. The percentage of time spent in the region immediately surrounding the platform locations during pre-training, mass training, and a non-trained area were compared. Both controls and CPP rats displayed a preference for the area surrounding the mass trained platform. (C) A 30-s probe test 8 h after mass training for group 1 in Experiment 1. The percentage of time spent in the pre-trained quadrant, mass trained quadrant and the average of the other two was compared. Controls displayed no preference whereas CPP rats displayed a preference for the pre-trained quadrant. (D) A 30-s probe test 8 h after mass training for group 1 in Experiment 1. The percentage of time spent in the region immediately surrounding the platform locations during pre-trained, mass trained and a non-trained area were compared. Controls displayed a preference for the area immediately surrounding the mass trained platform whereas CPP rats displayed a preference for the area surrounding the pre-trained platform. Error bars 1 ± SE, ^∗p < 0.05.