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. 2019 Feb 26;10:133. doi: 10.3389/fphar.2019.00133

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Copyright © 2019 Boudieu, Mountadem, Lashermes, Meleine, Ulmann, Rassendren, Aissouni, Sion, Carvalho and Ardid.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of PGB (30 mg kg^-1, s.c.) on spleen (A) and bladder (B) weight, mucosal thickness (C,D) and bladder MPO activity (E) in cyclophosphamide (CYP)-induced cystitis in mice. The values are expressed as a mean ±S.E.M. and compared by a 1-way ANOVA (Treatment) followed by Tukey post hoc test for multiple comparisons. For panels A, B, E, the result represented n = 8 animals / group and for panel C, 4 measured per section and 3 sections per animals were analyzed. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001 vs. control group.