Table 2.

The significance probability (p - value; F- ratio), lack of fit and coefficients of determination of second order polynomial models that demonstrated the relationship between the experimental and response factors as refined by the BBD.

OPE		Linear effects			Linear interactions			Quadratic interactions			Model	LOF	r 2	$r_{adj}^2$
		A	B	C	AB	AC	BC	AA	BB	CC
TEP	RC	−6578.31	−5362.24	68725.90	−41.71	67.82	−1.24	−86.11	−128.51	−123.33	−8.54E6		0.9090	0.7453
	F-ratio	2.51	7.41	0.18	1.08	0.40	0.00	1.07	37.96	0.69		5.69
	p-value	0.1741	0.0417	0.6885	0.3457	0.5536	0.9823	0.3493	0.0016	0.4435	0.0368	0.1570
TPP	RC	−20214.10	21629.90	192765.00	3.94	224.25	−71.02	−266.10	−127.83	−355.49	−2.32E7		0.7661	0.3450
	F-ratio	4.43	4.40	0.03	0.00	0.61	0.25	1.41	5.21	0.80		1.36
	p-value	0.0893	0.0901	0.8646	0.9722	0.4699	0.6416	0.2882	0.0713	0.4129	0.2641	0.4840
TNBP	RC	−7979.85	21520.60	131141.00	41.30	139.35	−70.44	−189.86	−54.09	−241.67	−1.59E7		0.7720	0.3615
	F-ratio	4.42	7.47	0.02	0.31	0.50	0.51	1.51	1.96	0.77		0.91
	p-value	0.0895	0.0412	0.9000	0.6018	0.5127	0.5083	0.2737	0.2202	0.4191	0.2520	0.6070
TCEP	RC	7444.20	4191.35	11763.40	30.20	1.54	−13.45	−40.86	−6.84	−20.55	−1.42E6		0.9404	0.8332
	F-ratio	13.48	53.65	0.06	6.93	0.00	0.77	2.93	1.31	0.23		2.00
	p-value	0.0144	0.0007	0.8197	0.0463	0.9619	0.4194	0.1477	0.3037	0.6488	0.0139	0.3710
TCIPP	RC	−23.90	3572.82	12392.20	7.90	13.15	−12.09	−21.58	−3.74	−23.40	−1.45E6		0.7846	0.3969
	F-ratio	4.83	8.45	0.06	0.89	0.35	1.17	1.53	0.73	0.57		0.74
	p-value	0.0794	0.0335	0.8237	0.3896	0.5822	0.3291	0.2716	0.4310	0.4850	0.2264	0.6720
TDCIPP	RC	2997.13	2853.14	12686.90	11.21	2.32	−8.71	−19.84	−4.52	−21.63	−1.77E6		0.9553	0.8747
	F-ratio	15.32	75.02	1.58	5.42	0.03	1.84	3.92	3.25	1.47		1.77
	p-value	0.0113	0.0003	0.2645	0.0673	0.8636	0.2326	0.1046	0.1313	0.2789	0.0070	0.4040
TBOEP	RC	5088.09	1724.69	8810.79	17.75	−4.76	−5.82	−17.27	−3.39	−13.68	−1.37E6		0.9724	0.9228
	F-ratio	30.49	114.02	5.20	18.73	0.19	1.13	4.10	2.52	0.81		3.46
	p-value	0.0027	0.0001	0.0715	0.0075	0.6816	0.3360	0.0989	0.1730	0.4085	0.0022	0.2410
TPHP	RC	11657.50	14648.60	71805.70	50.75	12.85	−47.80	−79.65	−16.74	−121.79	−1.02E7		0.9334	0.8134
	F-ratio	12.35	43.24	2.51	4.39	0.04	2.19	2.50	1.77	1.85		1.09
	p-value	0.0170	0.0012	0.1740	0.0902	0.8500	0.1987	0.1748	0.2414	0.2321	0.0180	0.5520
EHDPP	RC	45358.80	21252.60	135283.00	155.24	−12.61	−71.20	−224.65	−39.05	−229.32	−1.93E7		0.9714	0.9200
	F-ratio	28.33	110.25	1.02	16.13	0.01	1.91	7.79	3.77	2.57		1.87
	p-value	0.0031	0.0001	0.3584	0.0102	0.9074	0.2256	0.0384	0.1099	0.1698	0.0024	0.3890
TEHP	RC	12887.70	77284.80	417801.00	306.78	343.72	−261.83	−670.97	−113.61	−752.44	−5.49E7		0.9354	0.8193
	F-ratio	11.92	41.94	0.52	5.34	0.94	2.19	5.90	2.71	2.35		1.64
	p-value	0.0182	0.0013	0.5017	0.0687	0.3760	0.1990	0.0595	0.1609	0.1860	0.0167	0.4260

RC: Regression coefficient, A, B and C are the experimental factors, desorption flow, cryofocusing temperature and cryodesorption temperature, respectively. LOF refers to Lack of fit.