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. 2019 Feb 26;10:183. doi: 10.3389/fimmu.2019.00183

Table 1.

Characterization of cultured cells for 6 weeks.

GM-CSF/SCF G-CSF/SCF M-CSF/SCF
Level of HLA-DR low low high Figure 1F
CD11b+CD33+ high dim high Figure 1D
Monocyte (CD14):Granulocytes(CD15) ratio 9: 1 (M-MDSCs) 2: 8 10:0 Figure 1F
Level of Arginase 1 and IDO +++ + ++ Figure 3A
Suppressive activity +++ ++ + Figure 4A
Treg induction +++ ++ ++ Figure 4B

Typical nomenclature of human myeloid derived suppressor cells (MDSCs): HLA-DRnegative or low, CD11b+CD33+, CD14+: Monocytic MDSCs (M-MDSCs). HLA-DRnegative or low, CD11b+CD33+, CD15+: Granulocytic MDSCs (G-MDSCs).