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. 2019 Mar 5;11(1):10. doi: 10.1038/s41368-018-0043-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — The shift in microbial composition after cohousing. a PCoA score plot of the microbiota from each gut segment of HOMA mice, HMA mice and cohoused mice. b PCoA score plot of the microbiota from each gut segment from HMA mice and cohoused mice. c HMA mouse-enriched genus-level taxa in the stomach are indicated by a positive LDA score (green), while the cohoused (C) mouse-enriched taxa have a negative LDA score (red). d The HMA mouse-enriched genus-level taxa in the small intestine are indicated by a positive LDA score (green), while the cohoused mouse-enriched taxa have a negative LDA score (red). e The HMA mouse-enriched genus-level taxa in the caecum are indicated by a positive LDA score (green), while the cohoused mouse-enriched taxa have a negative LDA score (red). f The HMA mouse-enriched genus-level taxa in the colon are indicated by a positive LDA score (green), while the cohoused mouse-enriched taxa have a negative LDA score (red). g Microbial Source Tracker analysis showed the proportions of the different sources present in the microbiota of the cohoused mice in each gut segment. The Kruskal–Wallis test was used to compare the proportions of the oral sources present in each gut segment of the cohoused mice (*P < 0.05, **P < 0.01)