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ACVR1 R206H and H3.3K27M significantly increase tumor grade
| Virus combination | p value |
|---|---|
| ACVR1 R206H; H3.3K27M vs ACVR1 WT; H3.1 WT | 0.0052** |
| ACVR1 R206H; H3.3K27M vs ACVR1 R206H | 0.0021** |
| ACVR1 R206H; H3.3K27M vs RCAS Y | 0.0172* |
| ACVR1 R206H; H3.3K27M vs ACVR1 WT | 0.0307* |
| ACVR1 R206H; H3.3K27M vs BMP4 | 0.0172* |
| ACVR1 R206H; H3.3K27M vs H3.1K27M | 0.0237* |
*p < 0.05; **p < 0.01, Fisher's exact test
