Table 2.
Identification of potent P. a. ATCC 10145-cidal HRNR2591–2684 peptide fragments.
AA-sequence | Net charge* | Name | n | LD90 (µg/ml) | LD100 (µg/ml) |
---|---|---|---|---|---|
HGSRSGQSSRGERHGSSSGSSSH | +5 | HR 1-11, HRNR2606–2628 | 2 | 0.075 | 2.35 |
GRHGSGLGHSSSHGQHGSGSGRSSSRGPY | +7 | HR 1-17, HRNR2656–2684 | 2 | 0.038 | 0.15 |
GRHGSGLGHSSSHGQHGSGSGR | +6 | HR 1-18, HRNR2656–2677 | 7 | 0.038 | 0.15 |
Test condition: 10 mM NaP, pH 5.5 and 0.25% glucose. *At pH 5.5. The results shown are representatives. n: number of experiments.