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. 2019 Mar 4;10:28. doi: 10.1186/s13244-019-0703-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — A 69-year-old man with Gleason 4 + 3 prostate cancer (white arrows). Diffusion signal evaluated using different models of analysis: mono-exponential (a) intravoxel incoherent exponential model (IVIM) (b), diffusion kurtosis imaging (DKI) (c), and diffusion tensor imaging (DTI) (d). DWI can offer multiple parameters depending on the model of analysis, including ADC, perfusion fraction (f), or apparent kurtosis (Kapp) with a different biological meaning. Biological and physiological correlation of parameters obtained from analysis is not entirely clear and their clinical value may depend on tumor type