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. 2019 Feb 26;13:172. doi: 10.3389/fnins.2019.00172

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Copyright © 2019 Joksimovic, Selakovic, Jovicic, Mitrovic, Mihailovic, Katanic, Milovanovic and Rosic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serum αMSH and hippocampal MC4R content. (A) Serum αMSH levels; (B) Distribution of immunoreactive MC4R neurons in hippocampus; (C–F) Number of MC4R immunoreactive neurons in CA1 (C), CA2/3 (D), DG (E) and total hippocampal section (F); (C, control group; E, exercise group; N, nandrolone-decanoate group; E+N, exercise plus nandrolone-decanoate group; T, testosterone-enanthate group; E+T, exercise plus testosterone-enanthate group). Bars represent means ± SEM, ^∗ denotes a significant difference p ≤ 0.025, ^∗∗ denotes a significant difference p ≤ 0.01.