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. 2019 Feb 26;10:233. doi: 10.3389/fpls.2019.00233

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Copyright © 2019 Hung, Chen, Li, Chen, Chen, Cui and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A model for LDL1/2 and HDA6 functions in the regulation of core circadian clock components. Both morning accumulated CCA1/LHY and evening accumulated TOC1 interact with the same histone modification complex containing LDL1/2 and HDA6. CCA1/LHY act as transcription repressors and recruit the histone modification complex to their target loci such as TOC1 in the morning. Meanwhile, TOC1 also recruits the histone modification complex to its targets such as CCA1 and LHY in the evening.