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. 2019 Feb 26;10:147. doi: 10.3389/fphys.2019.00147

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Copyright © 2019 Li, Morvaridi, Lam, Chheda, Kamata, Katsumata, Edderkaoui, Yuan, Nissen, Pandol and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Matriptase expression is upregulated in PanIN, primary PDAC and liver metastasis. IHC analysis of normal human pancreatic tissues using anti-matriptase antibody. Representative staining images are shown. (A) Normal pancreas, PanIN1/2, PanIN 3, and PDAC; (B) Specimen of pancreatic cancer liver metastasis. The areas of the tumor and the adjacent tumor are indicated. Magnification: 4× (left panel) or 20×; Scale bar: 500 (left panel) or 100 μm.