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. 2019 Jan 28;60(3):464–474. doi: 10.1194/jlr.S091744

TABLE 2.

1. Rx100 has favorable drug profile including drug substance stability ≥5 years at refrigerated temperatures

Chemical formula C18H37O3SP
Molecular weight 364.52
Salt form L-Lysine
Aqueous solubility >250 mg/ml
EC50 at human LPA1/2/3/4/5 (nM) in Ca2+ mobilization assay 850, 23, 120, 950, 3
Pharmacokineticsa T1/2 10.5 h
a

In Rhesus macaques.