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Pyriproxyfen metabolism by mosquito P450s.
| P450 | % PPF depletion |
Inhibition ratio (%)a | |
|---|---|---|---|
| −PBO | + PBO | ||
| CYP6M2 | 30.93 ± 4.65 | 1.44 ± 0.67 | 95.3 |
| CYP6P2 | 58.03 ± 1.35 | 6.45 ± 3.22 | 91.0 |
| CYP6P3 | 100.0 ± 0.01 | 8.68 ± 1.74 | 91.3 |
| CYP6P4 | 81.63 ± 0.63 | 4.44 ± 1.99 | 94.6 |
| CYP6P5 | 39.96 ± 1.04 | 2.40 ± 2.01 | 95.4 |
| CYP9J5 | 24.78 ± 2.13 | 0.08 ± 0.15 | 99.6 |
| CYP6Z2 | 66.26 ± 3.02 | 8.41 ± 1.58 | 87.3 |
Reduction of PPF depletion in percentage caused by the inhibitory effect of PBO; (mean ± SD).
