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. 2019 Mar 1;7:2050313X19834425. doi: 10.1177/2050313X19834425

Table 1.

Case reports of acute leukemia presenting as Fournier’s gangrene: demographics, blood counts, culture data, leukemia with time of diagnosis, treatment course, and outcomes.

Age Sex Blood counts Culture data Leukemia details Treatment Outcome Reference
50 years Male WBC: 10.5 × 103/mm3
Hgb: 7.7 g/dL
Plt: 17 × 103/mm3
Myeloblasts: 49%
Surgical (E. coli)
Blood (negative)
Urine (negative)
Acute promyelocytic
Postmortem
Ciprofloxacin
Clindamycin
Penicillin G
Death Oiso et al.13
33 years Male WBC: 1.9 × 103/mm3
Hgb: 8 g/dL
Plt: 50 × 103/mm3
Myeloblasts: NR
Surgical (Bacteroides fragilis)
Blood (B. fragilis)
Acute myelomonocytic
After antibiotic initiation by 1 week
Antibiotics NR
Chemotherapy
Death with chemotherapy induction Islamoglu et al.12
4 days Female WBC: 2.1 → 18.5 × 103/mm3
Hgb: 8.8 g/dL
Plt: 21 × 103/mm3
Myeloblasts: 0% → 52%
Surgical (Pseudomonas aeruginosa)
Blood (P. aeruginosa)
Acute myelogenous
After antibiotic initiation, timing NR
Meropenem
Vancomycin
Chemotherapy declined
Death Mosayebi et al.14

WBC: white blood cells; Hgb: hemoglobin; Plt: platelets; NR: not reported.