Fig. 1.

The suppressive effects of Resv on the differentiation of CD4⁺T cells into effector T cells. (a) Representative figure of flow cytometry using CD4⁺T stained with anti-IFN-γ FITC, anti-IL-17 PE and anti-IL-4 APC. The effect of Tac with or without Resv on (b) Th1 (IFN-γ⁺/CD4⁺ T cells), (c) Th2 (IL-4⁺/CD4⁺ T cells) (d) Th17 (IL-17⁺/CD4⁺ T cells) and (e) Treg (CD25⁺Foxp3⁺/CD4⁺ T cells) under Th0 polarizing conditions. *P < 0.05 vs. Th0 polarizing ^†P < 0.05 vs. Tac 1 ng/mL group ^‡P < 0.05 vs. Tac 10 ng/mL group §P < 0.05 vs. Tac 1 ng/mL + Resv 25 μM group. Resv, Resveratrol; Tac, tacrolimus; Treg, regulatory T cells