Table 2.
Candidate regions associated with fatty acid composition and fatty acid groups
| Trait | SNP name | BTA | Position | SNPa | MAF | P-value | SNP effectb | SE | PCGc |
|---|---|---|---|---|---|---|---|---|---|
| Saturated FA | |||||||||
| C22:0 | BovineHD0600017622 | 6 | 63657334 | G/A | 0.342 | 5.80E-07 | 0.002212982 | 0.000454901 | – |
| Monounsaturated FA | |||||||||
| C14:1 cis-9 | BovineHD2600005461 | 26 | 21140458 | G/A | 0.3791 | 1.72E-07 | −0.116976244 | 0.0247878 | SCD |
| C14:1 cis-9 | BovineHD2600005464 | 26 | 21144884 | G/A | 0.3764 | 2.62E-07 | −0.114923399 | 0.0247513 | SCD |
| C14:1 cis-9 | BovineHD2600005466 | 26 | 21146794 | G/A | 0.3984 | 1.02E-07 | −0.118178451 | 0.0242669 | SCD |
| C14:1 cis-9 | BovineHD2600005465 | 26 | 21146019 | G/A | 0.397 | 1.22E-07 | −0.117257801 | 0.0241962 | SCD |
| C18:1 cis-9 | BovineHD0600017761 | 6 | 64216527 | A/G | 0.0989 | 2.90E-07 | −2.77403258 | 0.55471 | – |
| C18:1 cis-9 | BovineHD0600017773 | 6 | 64280345 | C/A | 0.1511 | 4.12E-07 | −2.356278809 | 0.477168 | – |
| C20:1 cis-11 | BovineHD0800012682 | 8 | 42650702 | G/A | 0.05769 | 4.89E-07 | 0.105893342 | 0.00215886 | SMARCA2 |
| Polyunsaturated FA | |||||||||
| C22:6 n-3 | BovineHD0100034705 | 1 | 122808627 | G/A | 0.364 | 3.38E-10 | 0.004481756 | 0.00137556 | PLSCR5 |
| C22:6 n-3 | BovineHD0200040673 | 2 | 73693578 | G/A | 0.0728 | 9.19E-08 | 0.007072896 | 0.00233111 | CLASP1 |
| C22:6 n-3 | BovineHD0300010307 | 3 | 33051872 | A/G | 0.06319 | 1.31E-07 | 0.007624579 | 0.0025411 | CYM |
| C22:6 n-3 | BovineHD1000015166 | 10 | 50404371 | A/C | 0.1456 | 4.86E-08 | 0.005148315 | 0.00176711 | – |
| C22:6 n-3 | BovineHD1000029857 | 10 | 102483257 | A/C | 0.1181 | 3.48E-07 | 0.005129722 | 0.00198152 | – |
| C22:6 n-3 | BovineHD1400018498 | 14 | 66120964 | A/G | 0.1168 | 8.09E-08 | 0.005746942 | 0.0019963 | – |
| C22:6 n-3 | BovineHD2800003012 | 28 | 9852321 | A/G | 0.06044 | 3.59E-07 | −0.006883573 | 0.00246427 | – |
| Fatty acid groups | |||||||||
| SFA | BovineHD0600017761 | 6 | 64216527 | A/G | 0.0989 | 4.29E-07 | 2.276282318 | 0.454104 | – |
| PUFA | BovineHD0500031844 | 5 | 110438965 | A/G | 0.06456 | 3.26E-07 | 0.629658268 | 0.126903 | BAIAP2L2, MAFF, TMEM184B |
| MUFA | BovineHD0600017761 | 6 | 64216527 | A/G | 0.0989 | 8.95E-08 | −2.641123459 | 0.505798 | – |
| MUFA | BovineHD0600017773 | 6 | 64280345 | C/A | 0.1511 | 4.43E-07 | −2.15015271 | 0.436519 | – |
| n-6 | BovineHD0500031844 | 5 | 110438965 | A/G | 0.06456 | 1.21E-07 | 0.5470253 | 0.148374 | BAIAP2L2, MAFF, TMEM184B |
| PUFA/SFA | BovineHD0500031844 | 5 | 110438965 | A/G | 0.06456 | 5.56E-07 | 0.01371442 | 0.00280407 | BAIAP2L2, MAFF, TMEM184B |
| PUFA/SFA | BovineHD0900022545 | 9 | 81183556 | G/A | 0.07005 | 5.48E-07 | 0.012964716 | 0.00264927 | MIR2284AA-4 |
| PUFA/SFA | BovineHD1500021109 | 15 | 73179761 | A/C | 0.4931 | 7.80E-08 | −0.007313559 | 0.0013969 | – |
aminor allele/ major allele
bThe SNP effect was the additive effect calculated by FarmCPU
cPositional/putative candidate gene