Fig. 3.

Histopathologic findings of the posterior segment OU were consistent with chronic glaucoma. a OS: There is severe diffuse inner to segmental full thickness retinal atrophy. In regions of full thickness retinal atrophy, which affects the nontapetal retina, there is loss of neurons from all layers, marked architectural collapse and thinning, and multifocal infiltrates of pigmented cells into the neural retina. b OD: There is diffuse inner to segmental full thickness retinal atrophy. In areas of inner retinal atrophy, which affects the tapetal retina, there is variable loss of neurons from the ganglion and inner nuclear layers, variable blending of the inner and outer nuclear layers, and variable rarefaction and collapse of the nerve fiber and plexiform layers. c OS: The optic nerve head is markedly cupped with rarefaction and mild gliosis. Cavitations within the optic nerve head contain accumulations of flocculent basophilic material, consistent with Schnabel’s cavernous atrophy. Hematoxylin and eosin (H&E) stain. Scale bar in A and B = 25 μm and C = 160 μm