Table 2.
Candidate tumor suppressor gene | Gleason Score (GS) | ||||
---|---|---|---|---|---|
GS = 6 | GS = 7 | GS = 8 | GS = 9 | GS = 10 | |
IKZF1 | No sig | No sig | No sig | No sig | Up |
PPM1A | No sig | No sig | No sig | Down | Down |
FBP1 | Up | Up | Up | Up | Down |
SMCHD1 | No sig | Down | No sig | No sig | Up |
ALPL | Down | Down | Down | Down | Down |
CASP5 | Down | Down | No sig | Down | No sig |
PYHIN1 | No sig | No sig | No sig | No sig | Up |
DAPK1 | Up | Up | Up | Up | Up |
CASP8 | No sig | Up | Up | Up | Up |
Up: up-regulated; down: down-regulated; no sig: no significant