Table 3.
GO terms analysis of aberrantly methylated-differentially expressed genes in PCa
| Category | Term | P-value |
|---|---|---|
| Hypermethylation-low expression | Cytokine-mediated signaling pathway | 1.38E−04 |
| Benzene-containing compound metabolic process Kynurenine metabolic process |
3.36E−04 | |
| Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 3.36E−04 | |
| Indolalkylamine catabolic process | 3.78E−04 | |
| Response to vitamin | 4.19E−04 | |
| Cellular response to mechanical stimulus | 4.19E−04 | |
| Tryptophan catabolic process | 4.72E−04 | |
| Tryptophan metabolic process | 5.11E−04 | |
| Positive regulation of transcription, DNA-templated | 5.11E−04 | |
| Hypomethylation-high expression | Regulation of transforming growth factor beta2 production | 1.43E−02 |
| Regulation of receptor recycling | 6.14E−04 | |
| Membrane raft assembly | 1.43E−02 | |
| Telencephalon cell migration | 1.43E−02 | |
| Regulation of endothelial cell chemotaxis to fibroblast growth factor | 1.63E−02 | |
| Positive regulation of vesicle fusion | 1.43E−02 | |
| Negative regulation of protein depolymerization | 8.40E−04 | |
| Positive regulation of receptor binding | 1.43E−02 | |
| Nodal signaling pathway | 1.83E−02 | |
| Positive regulation of vascular endothelial cell proliferation | 2.03E−02 |