Table 2.
Comparison of the mean numbers of risk and alternative alleles per person in E3 homozygotes vs other controls. APOE region is excluded
SNP selection threshold | E3 homozygotes | Other genotypes | OR | P | ||
---|---|---|---|---|---|---|
Mean No of risk alleles | Mean No of alternative alleles | Mean No of risk alleles | Mean No of alternative alleles | |||
0.0001 | 87.6 | 66.8 | 88.4 | 67.7 | 0.991 | 1.00 |
0.001 | 293.8 | 293.2 | 292.8 | 295.4 | 1.003 | 0.973 |
0.01 | 1727.4 | 1621.3 | 1723.0 | 1623.0 | 1.003 | 0.961 |
0.05 | 7181.6 | 6461.3 | 7153.8 | 6471.3 | 1.004 | 0.833 |
0.1 | 13070.4 | 11836.9 | 13037.7 | 11860.3 | 1.003 | 0.810 |
0.2 | 23540.4 | 21344.5 | 23466.5 | 21388.0 | 1.003 | 0.703 |
0.3 | 32649.2 | 29969.2 | 32573.0 | 30039.3 | 1.002 | 0.684 |
0.4 | 41028.5 | 37805.2 | 40983.2 | 37869.4 | 1.001 | 0.785 |
0.5 | 48618.4 | 45048.2 | 48564.7 | 45118.6 | 1.001 | 0.776 |