Table 4.
Correlations between the CD1a-positive Langerhans cell (LC) counts in the lining epithelia or in the subepithelial connective tissues of 60 odontogenic keratocyst (OKC) samples and clinical parameters of 60 OKC patients.
| Parameter | Mean CD1a-positive LC count ± SD (cells/high-power field) |
|||||
|---|---|---|---|---|---|---|
| Lining epithelium |
Subepithelial connective tissue |
|||||
| Severe | Mild/moderate | None | Severe | Mild/moderate | None | |
| Gender | ||||||
| Male (n = 33) | 10.0 ± 4.6 (n = 8) | 4.8 ± 2.6 (n = 22) | 0.5 ± 0.4 (n = 33) | 10.7 ± 6.0 (n = 8) | 3.2 ± 2.8 (n = 22) | 0.2 ± 0.3 (n = 33) |
| Female (n = 27) | 17.0 ± 4.5 (n = 5) | 6.0 ± 2.2 (n = 17) | 0.5 ± 0.4 (n = 27) | 7.0 ± 9.1 (n = 5) | 1.7 ± 2.5 (n = 17) | 0.2 ± 0.3 (n = 27) |
| aP-value | 0.021 | 0.148 | 0.944 | 0.398 | 0.086 | 0.765 |
| Age (yr) | ||||||
| ≤ 25 (n = 25) | 13.4 ± 2.8 (n = 4) | 5.3 ± 2.7 (n = 14) | 0.5 ± 0.3 (n = 25) | 12.4 ± 8.3 (n = 4) | 3.3 ± 3.4 (n = 14) | 0.2 ± 0.3 (n = 25) |
| > 25 (n = 35) | 12.4 ± 6.6 (n = 9) | 5.4 ± 2.4 (n = 25) | 0.5 ± 0.4 (n = 35) | 7.8 ± 6.7 (n = 9) | 2.1 ± 2.2 (n = 25) | 0.2 ± 0.3 (n = 35) |
| aP-value | 0.776 | 0.873 | 0.723 | 0.314 | 0.225 | 0.852 |
| Location | ||||||
| Maxilla (n = 23) | 12.8 ± 5.0 (n = 7) | 5.5 ± 2.5 (n = 16) | 0.5 ± 0.4 (n = 23) | 12.2 ± 6.7 (n = 7) | 3.2 ± 3.5 (n = 16) | 0.3 ± 0.4 (n = 23) |
| Mandible (n = 37) | 12.6 ± 6.8 (n = 6) | 5.2 ± 2.5 (n = 23) | 0.5 ± 0.4 (n = 37) | 5.8 ± 6.7 (n = 6) | 2.1 ± 1.9 (n = 23) | 0.1 ± 0.2 (n = 37) |
| aP-value | 0.959 | 0.689 | 0.720 | 0.114 | 0.187 | 0.034 |
| Size (cm) | ||||||
| ≤ 3 cm (n = 28) | 12.0 ± 5.7 (n = 6) | 4.9 ± 2.9 (n = 17) | 0.6 ± 0.3 (n = 28) | 12.7 ± 7.4 (n = 6) | 3.3 ± 3.3 (n = 17) | 0.2 ± 0.3 (n = 28) |
| > 3 cm (n = 32) | 13.3 ± 5.9 (n = 7) | 5.7 ± 2.1 (n = 22) | 0.5 ± 0.4 (n = 32) | 6.3 ± 6.0 (n = 7) | 2.0 ± 2.1 (n = 22) | 0.2 ± 0.3 (n = 32) |
| aP-value | 0.713 | 0.339 | 0.326 | 0.109 | 0.119 | 0.910 |
| Recurrence | ||||||
| With (n = 6) | 15.0 ± 0.0 (n = 1) | 3.7 ± 2.6 (n = 4) | 0.5 ± 0.4 (n = 6) | 2.4 ± 0.0 (n = 1) | 2.4 ± 2.4 (n = 4) | 0.1 ± 0.2 (n = 6) |
| Without (n = 54) | 12.5 ± 5.8 (n = 12) | 5.4 ± 2.4 (n = 35) | 0.5 ± 0.4 (n = 54) | 9.7 ± 6.9 (n = 12) | 2.5 ± 2.8 (n = 35) | 0.2 ± 0.3 (n = 54) |
| aP-value | 0.688 | 0.184 | 0.907 | 0.334 | 0.966 | 0.653 |
a
Comparison of mean CD1a-positive LC counts between two different groups by Student's t-test.