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Surface topographical feature of PDMS substrates characterized by AFM. (A) Flat PDMS, (B) PDMS with micro-gratings, (C) Analysis of grating depth (5 μm), width (15 μm) and pitch (30 μm) using NanoScope analysis software v1.40. The micro-gratings were successfully transferred from silicon wafer mold to PDMS. (D) Schematic representation of dopamine polymerization and different possible chemical interactions between PD and collagen.
