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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Sex Transm Dis. 2019 Feb;46(2):80–85. doi: 10.1097/OLQ.0000000000000910

Table 1.

Ocular Syphilis (OS) prevalence by HIV status within demographic and clinical characteristic groups among syphilis patients reported in North Carolina, 2014-2016.

TOTAL HIV-Positive HIV-Negative HIV Unknown Status OS Prevalence in HIV-Positive versus HIV-Negative/Unknown Status

N N Prevalence of OSa (%) N Prevalence of OSa (%) N Prevalence of OSa (%) Prevalence Ratio 95% Confidence Interval
TOTAL 7123 2846 2.1 3197 1.2 1080 1.1 1.8 1.2, 2.6

Gender

Male 5913 2790 2.1 2313 1.5 810 0.9 1.6 1.1, 2.4
Female 1177 43 0.0 870 0.5 264 1.9 NA NA
Transgender 33 13 0.0 14 0.0 6 0.0 NA NA

Race

Black 4499 1909 1.4 1986 0.8 604 1.0 1.6 0.9, 2.8
White 1852 704 4.1 825 2.1 323 1.6 2.2 1.3, 3.7
Other 759 230 1.7 385 1.0 144 0.7 1.8 0.5, 6.8
Missing 13 3 0.0 1 100.0 9 0.0

Age

<40 years 4886 1910 1.3 2302 0.4 674 0.0 3.9 1.9, 8.1
≥40 years 2237 936 3.6 895 3.1 406 3.0 1.2 0.8, 1.9

MSM Riskb

MSM 4018 2286 2.1 1377 1.0 355 0.3 2.4 1.4, 4.3
Non-MSM 1895 504 2.2 936 2.1 455 1.3 1.2 0.6, 2.4

Syphilis Stage

Primary & Secondary 2932 1196 2.0 1318 1.1 418 0.2 2.3 1.2, 4.4
Non-Primary/Non-Secondary Early 1959 962 0.7 820 0.7 177 0.6 1.0 0.4, 2.9
Late or Unknown Duration 2232 688 4.1 1059 1.7 485 2.1 2.2 1.3, 3.8

Previous Syphilis Diagnosis

No 5891 2009 2.5 2898 1.1 984 0.9 2.4 1.6, 3.6
Yes 1232 837 1.0 299 2.0 96 3.1 0.4 0.2, 1.1

Year Diagnosed

2014 1788 694 1.7 746 0.9 348 0.3 2.4 1.0, 5.8
2015 2659 1087 2.1 1189 1.4 383 0.8 1.7 0.9, 3.0
2016 2676 1065 2.3 1262 1.1 349 2.3 1.7 0.9, 2.9

Total Non-OS OS Non-OS OS Non-OS OS

Median Age (IQRd) 31 (25-43) 32 (26-44) 44 (32-50) 29 (23-41) 48 (36-56) 33 (25-46) 54 (50-62)
Median RPRc (IQRd) 1:32 (1:8-1:128) 1:64 (1:16-1:128) 1:128 (1:64-1:512) 1:32 (1:8-1:64) 1:96 (1:48-1:256) 1:32 (1:4-1:64) 1:64 (1:8-1:128)
a.

per 100

b.

Among men only

c.

RPR=Rapid plasma regain titer, a serologic test to screen for syphilis. The titer refers to the greatest dilution of serum at which the test is still positive. [18]

d.

IQR=Interquartile Range