Table 2.
MICs of essential oils (EOs), petroleum ether extracts (PEEs), dichloromethane extract (DCME), isolated sesquiterpenes, and synthetic derivates from P. uviferum on S. aureus strains.
| Sample | MIC (μg/mL) | ||
|---|---|---|---|
| WT | SA-K1902 | SA-K2378 | |
| Extracts | |||
| EO | 62.5 | 31.3 | 62.5 |
| PEE | 31.3 | 31.3 | 31.3 |
| DCME | 62.5 | 62.5 | 125 |
| Isolated compounds | |||
| Trans-calamenene (1) | 125 | 125 | 125 |
| Cadalene (2) | 500 | 62.5 | 500 |
| Cubenol (3) | 62.5 | 62.5 | 125 |
| Epi-cubenol (4) | 31.3 | 62.5 | 125 |
| Torreyol (5) | i | i | i |
| 15-Copaenol (6) | 31.3 | 62.5 | 31.3 |
| Synthetic derivatives | |||
| 15-Copaenal (6OX) | 500 | 62.5 | 250 |
| 15-Copaenyl acetate (6AC) | 125 | 62.5 | 500 |
WT, wild type (NCTC 8325-4); K1902, norA-deleted; K2378, overexpressing norA; i, inactive.