Table 2.
Characteristic | Overall (n = 35) n (%) | Arm A (n = 17) n (%) | Arm B (n = 18) n (%) |
Age, years | |||
Median (range) | 60 (46–76) | 64 (49–76) | 59 (46–74) |
ECOG Performance Status | |||
0 | 23 (66) | 12 (71) | 11 (61) |
1 | 12 (34) | 5 (29) | 7 (39) |
Prior Anti-VEGF Agent | |||
Bevacizumab | 15 (43) | 5 (29) | 10 (56) |
Pazopanib | 11 (31) | 6 (35) | 5 (28) |
Sorafenib | 4 (11) | 2 (12) | 2 (11) |
Sunitinib | 5 (14) | 4 (24) | 1 (6) |
Time from Last Anti-VEGF Treatment, days | |||
Median (range) | 28 (10–76) | 26 (10–44) | 29 (13–76) |
# greater than 30 days | 14 (40) | 6 (35) | 8 (44) |
Number of Prior Regimens | |||
Median (range) | 3 (1–8) | 3 (1–6) | 3 (1–8) |
Gender | |||
Female | 8 (23) | 4 (24) | 4 (22) |
Male | 27 (77) | 13 (76) | 14 (78) |
Race/Ethnicity | |||
American Indian/AlaskaNative | 2 (6) | 2 (12) | 0 |
Asian/Pacific Islander | 1 (3) | 0 | 1 (6) |
Black | 3 (9) | 2 (12) | 1 (6) |
Hispanic | 8 (23) | 4 (24) | 4 (22) |
White | 21 (60) | 9 (53) | 12 (67) |