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. 2019 Feb 26;10:280. doi: 10.3389/fimmu.2019.00280

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Copyright © 2019 Petit, Bailey, Wheeler, de Oliveira, Forlenza and Wiegertjes.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Synteny analysis of mammalian CLR group V cluster on human chromosome 12 and mouse chromosome 6 shows partial conservation with zebrafish chromosome 16 and four carp scaffolds. Partial conservation of synteny between zebrafish chromosome 16 and the mammalian CLR group V cluster can be observed. Among the syntenic genes, two zebrafish CLTD-encoding genes are located, clec4c (NCBI Gene ID: 563797) and sclra (NCBI Gene ID: 564061). Synteny of zebrafish clec4c and sclra with Dectin-1, Dectin-2, and Mincle is highlighted by pink boxes. Synteny of carp cypCars is based on conservation of genes surrounding a CTLD-encoding gene for both clec4c and scrla. Large gaps between loci are indicated with breaks and chromosomal representations are not drawn to scale. Owing to the tetraploid nature of carp, two corresponding scaffolds for each zebrafish gene are shown.