Table 3.

Effect of antidiabetic drugs on the percentage of patients with hypoglycemia at baseline and week 52 of sitagliptin treatment

Antidiabetic drug	Baseline		Week 52
	FAS (n = 4,514)		FAS (n = 3,876)		With insulin (n = 354)		Without insulin (n = 3,522)
	Odds ratio	P‐value	Odds ratio	P‐value	Odds ratio	P‐value	Odds ratio	P‐value
Sulfonylurea	0.98	0.92	2.22	<0.001	1.10	0.79	4.01	<0.001
Glinide	1.66	0.51	2.05	0.26	0.83	0.86	4.14	0.07
α‐GI	0.68	0.13	0.74	0.28	0.72	0.35	0.73	0.49
Metformin	1.55	0.036	1.10	0.71	1.18	0.64	0.93	0.84
Pioglitazone	0.73	0.37	1.59	0.18	0.54	0.42	2.18	0.043
Insulin	11.59	<0.001	17.75	<0.001	–	–	–	–

Data are shown as odds ratio. α‐GI, alpha‐glucosidase inhibitor; FAS, full analysis set.